NMR is animportant and useful technique that is used in the pharmaceutical analysis.
Theprinciple of NMR is the nucleus of an atom in a magnetic field and exposed toelectromagnetic radiation resonate at a specific frequency of that radiation.That allows us to record a spectrum and obtain structural information about thesample. NMR uses radio frequency radiation, and its nuclei have a specificproperty. A Nuclei with an odd number of protons and or nuclei with an oddnumber of neutrons have this property and called spin, only nuclei that have aspin are detectable by NMR. The spin has a value that called (I) which caneither be integer or half integer. The nuclei with an odd number of protons andodd number of electrons have integer spin for example, 2H=1,6Li=1,10B=3.
On the other hand, nuclei with an odd number of protons or odd number ofelectrons have half integer spin such as, 13C=1/2, 1H=1/2,43Ca=7/2.Without an external applied magnetic field, a nucleus witha spin generate their magnetic field. When an external magnetic field(B0), ispresent the nuclei align their spin either with or against the field of theexternal magnet. There are several applications for NIR spectroscopy in thearea of routine control analysis, and it is useful to many industrial sectors,such as the environmental, agricultural, petrochemical, clinical, andpharmaceutical fields. For this practical, a qualitative assay is used topositively identify unknown powders, and a quantitative assay is used toconfirm the quantity of active ingredient in metoprolol tartrate tablets.