Abstract: proteomics ,trancriptomics.It is an advanced and executable technique

Abstract: Presently
scientist are innovatively using  ‘omics
approaches to screen  the toxicity of
chemicals, in different categories of potential chemicals depending upon their
mode of action.  Metabolomics is one of
those omics including proteomics ,trancriptomics.It  is an advanced
and executable technique  widely employed
to analyze the interactions of
organisms with their environment for studying  the stress induced by anthropogenic
activities. The pattern, or fingerprint, of metabolites (endogenous and exogenous low molecular mass chemicals
within a cell, tissue, or biofluid) of an organism in response to an external
to learn about the “health” of the organism. Pesticide  are sprayed on crops to help them grow, but
the effect on earthworms living in the soil under the plants is devastating, Pyrethroids
,subclass of pesticide ,are synthetic analogues of pyrethrins, which are
naturally produced by flowers of certain species of chrysanthemum  (Chrysanthemum cinerariaefolium). They are used
extensively for the control of arthropod pests of agricultural crops and
vectors of  animal and human disease. The
first commercial pyrethroids (discovered at Rothamsted), were
bioresmethrin,  permethrin, cypermethrin
and deltamethrin. In this review article ,we will be studying the effect on
earthworm metabolomics induced by pyrethroid use in agricultural land as
insecticide. Metabolomics has facilitated the identification of novel compounds
in earthworm tissue extracts which may be indicative of specific metabolism
changes resulting from chemical exposure.We will review the work studied on
some important biomarkers like aminoacids ,carbohydrates like glucose ,maltose
, IMP (inosine monophosphate ), HEFS
(2-hexyl-5-ethyl-3- furansulfonate) etc in earthworm’s different species. We
will focus on the different techniques which can be used to study the
metabolite profiles.